Chronic neuropathic pain affects millions worldwide, often resisting standard treatments and severely impacting quality of life. One lesser-known factor contributing to this persistent pain is the complex interaction between the autonomic nervous system (ANS) and somatic sensation. Research by Crossley C in 1995 sheds light on how these two systems interact pathologically, offering new perspectives on chronic neuropathic pain mechanisms. What Is Chronic Neuropathic Pain? Neur